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Signal Management Oversight

Explains the QPPV's oversight responsibilities in signal management, outlines the signal lifecycle (detection, validation, prioritisation, assessment, recommendation, communication), and links to related guides on QPPV responsibilities and inspection readiness.

Signal management is a core pharmacovigilance activity used to identify, evaluate and manage emerging safety information.

Role of the QPPV

The QPPV should maintain awareness of important signal management activities and associated governance processes.

Signal Lifecycle

Last reviewed: June 2026

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Last reviewed: 2026-06-07